Journal of Nuclear Agricultural Sciences ›› 2021, Vol. 35 ›› Issue (2): 349-356.DOI: 10.11869/j.issn.100-8551.2021.02.0349

• Induced Mutations for Plant Breeding·Agricultural Biotechnology • Previous Articles     Next Articles

Transmembrane Transport Regulation Mechanism of Monocarboxylate Transporter 1(MCT1) on the Alimentary Canal Epithelium

DONG Xianwen, FU Lin, ZHANG Li, ZHOU Peng, REN Hangxing, WANG Gaofu*   

  1. Chongqing Academy of Animal Sciences, Chongqing 402460
  • Received:2019-09-16 Online:2021-02-10 Published:2020-12-14

消化道上皮单羧酸转运蛋白1(MCT1)跨膜转运功能的调控机理

董贤文, 付琳, 张丽, 周鹏, 任航行, 王高富*   

  1. 重庆市畜牧科学院,重庆 402460
  • 通讯作者: *王高富,男,副研究员,主要从事反刍动物营养研究。E-mail:wanggaofs20031216@163.com
  • 作者简介:董贤文,男,主要从事反刍动物营养研究。E-mail:dxwcqxky@163.com
  • 基金资助:
    中国博士后科学基金面上项目(2019M653347),重庆市博士后科研项目特别资助(XmT2018001)

Abstract: The effective absorption of nutrients is important for efficient livestock production. Monocarboxylic acids are pivotal energy source, which are produced by microbial fermentation in digestive tract and absorbed primarily by monocarboxylate transporter 1 (MCT1). It is of fundamental importance to improve the livestock production performance by understanding the transport function and regulation mechanism of MCT1. The current review presented the gene and protein structure of MCT1, distribution and location of MCT1 in digestive tract, transport regulation mechanism of MCT1, aiming to provide a theoretical basis for future exploration of the transport function of MCT1.

Key words: alimentary canal epithelium, monocarboxylate 1, transport, regulation mechanism

摘要: 良好地吸收营养物质是家畜高效养殖的重要前提。单羧酸是饲粮在消化道发酵产生的重要供能物质,其吸收主要通过单羧酸转运蛋白(MCT1)来实现。深入研究MCT1的转运功能及调控机理对提高家畜生产性能具有重要意义。本文就MCT1的基因及蛋白结构特点、消化道分布与定位特点、转运机制和调控因素及机理进行综述,以期为MCT1的功能调控研究提供参考。

关键词: 消化道上皮, 单羧酸转运蛋白1, 转运, 调控机理